CHD. Reduction of total LDL-cholesterol, apolipoprotein B & triglycerides in the treatment of hyperlipidemia including hypercholesterolemia, adjunct therapy for homozygous familial hypercholesterolemia & ischemic heart disease.
CHD Initially, 20 mg once daily at bedtime, may increase at 4-wk intervals to max 80 mg/day. Hyperlipidemia 10-20 mg once daily at bedtime. Homozygous familial hypercholesterolemia 40 mg once daily at bedtime or 80 mg/day in 3 divided doses (20, 20 & 40 mg in the morning, afternoon & evening). Renal insufficiency 5-10 mg.
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